Navigating dysbiosis: Insights into gut microbiota disruption and health outcomes Gaurav

Authors

  • Gaurav N. Kasar Department of Pharmacology, Divine College of Pharmacy, Nashik 423301, India
  • Pooja B. Rasal Department of Pharmacology, JES's SND College of Pharmacy, Yeola 423401, India
  • Aman B. Upaganlawar Department of Pharmacology, SNJB's SSDJ College of Pharmacy, Nashik 423101, India
  • Durgesh S. Pagar Department of Pharmacology, Divine College of Pharmacy, Nashik 423301, India
  • Khemchand R. Surana Department of Pharmaceutical Chemistry, Divine College of Pharmacy, Nashik 423301, India
  • Sunil K. Mahajan Department of Pharmaceutical Chemistry, Divine College of Pharmacy, Nashik 423301, India 5Department of
  • Deepak D. Sonawane Department of Pharmaceutics, Divine College of Pharmacy, Nashik 423301, India

DOI:

https://doi.org/10.54844/cai.2024.0778

Keywords:

Dysbiosis, Microbiota, Fecal microbiota transplantation

Abstract

Dysbiosis is a condition of microbial imbalance marked by an overabundance of pathogenic microbes and decreased microbial diversity, which can seriously impair physiological functions. These factors all influence the composition and function of the gut microbiome. Dietary interventions are important, especially those that are high in fiber and prebiotics, which increase microbial diversity and encourage the growth of good bacteria. The effectiveness of fecal microbiota transplantation (FMT) in treating recurrent Clostridium difficile infections has drawn attention, and it is being investigated for additional dysbiosis-related illnesses. There are still issues, though, such as the absence of accepted diagnostic standards for dysbiosis, the variation in how each person reacts to treatments, and doubts about the long-term effects and safety of some treatments. The creation of reliable, standardized diagnostic instruments should be the top priority for future research directions in order to precisely diagnose dysbiosis and evaluate treatment results. Furthermore, the need for customized medicine strategies that use developments in microbiome analysis to customize interventions according to each patient's unique microbiome composition and medical state is increasing. Translating scientific discoveries into useful applications that improve gut health will require interdisciplinary partnerships between microbiologists, physicians, dietitians, and public health specialists.

Published

2025-06-20

How to Cite

1.
Kasar GN, Rasal PB, Upaganlawar AB, Pagar DS, Surana KR, Mahajan SK, Sonawane DD. Navigating dysbiosis: Insights into gut microbiota disruption and health outcomes Gaurav. Community Acquir Infect. 2025;12. doi:10.54844/cai.2024.0778

Issue

Section

Review Articles

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